Janet Hester Froome was raised in the Winton Place community in Cincinnati, Ohio, and graduated from Hughes High School in 1926. She attended Ohio Wesleyan University in Delaware, Ohio, for two years, and then transferred to the Ball Memorial Hospital School of Nursing at Ball State Teachers’ College in Muncie, Indiana. Froome graduated in 1936 and returned to Cincinnati to teach at the Jewish Hospital School of Nursing.
In August 1941, Froome joined the Army Nurse Corps as a second lieutenant. She reported to duty at Billings General Hospital at Fort Harrison, Indiana, and in February 1942, she received overseas orders. Froome sailed from New York City to Melbourne, Australia, and then was assigned to a hospital set up in Nudgee Junior College, a Catholic boy's school outside Brisbane. After a year, she was transferred to a hospital in Rockhampton, Australia. In mid-1944, Froome sailed to a hospital in Port Moresby, New Guinea. She soon became chief nurse at another hospital in Dobodura, New Guinea, and was promoted to first lieutenant and then captain. In December 1944, Froome returned to the United States and was assigned to Wakeman General Hospital in Indiana, where she took care of returning prisoners of war and a group of German POWs. She was discharged in December 1945.
Froome continued nursing at Jewish Hospital and in Muncie, and earned a master’s degree from Columbia University in New York City. She then spent one year at a children’s hospital in St. Paul, Minnesota, before returning to Jewish Hospital as the head of the nursing school. Froome later taught nursing at the University of Cincinnati, where she received a second master’s degree.